Wednesday, February 10, 2016

Clinical Uses of Medical Marijuana

There have been numerous studies of medical marijuana that prove its viability to treat certain medical conditions. But it has quite a difficult time to be approved as a drug for medical uses. However, these studies have presented possible medical uses. Other issues have questioned the effectiveness of marijuana in the field of medicine. Some people said that majority of marijuana in the US is derived from the black market, where agricultural standards were not applied during farming and harvesting.  The amount of THC (tetrahydrocannabinol) in a smoked marijuana can be viable, the reason why accurate dosage will be difficult to manage.
For most proponents, this form of marijuana is utilized to aid patients in dealing with different symptoms like nausea, chronic pain and depression. In the United States, medical marijuana is legally used to treat the following diseases:
Alzheimer’s Disease
Crohn’s disease
Wasting syndrome
Multiple sclerosis

A lot of countries including the Netherlands, Austria and Canada studied the potential uses of medical marijuana and legalized this for patient use. While in many countries the drugs have been very controversial, many proponents showed evidence that patients administered with the drug showed improvements. Like the other uses of medical marijuana, its analgesic properties of medical marijuana have been controversial as well. The opposition claims that federally legal analgesics are already in the market in the form of opiates and NSAIDS such as Advil. However, the proponents of the drug claim that the use of medical marijuana as analgesics does not have very harmful effects and has lesser chance of causing addition than opiates. While these opposing claims continue, there is the truth behind the property of the drug to be less physiologically addictive.
Marijuana has been proven to increase appetite and weight gain for HIV patients after smoking. The first human study that attested to this claim, specifically the craving of sweet food, was made in 1971. Since that time, there were other relevant studies conducted some of which found that marijuana users showed an increase in body weight.

Moreover, marijuana has been also proven to have antiemetic effects. Studies showed that it is effective to placebo in nausea as a result from chemotherapy that induced moderate emesis. There are also previous reports that stated the potential of marijuana to have antitremor, antispasmodic and antiataxic activity. These properties have been studied in peopled with Parkinson’s disease, multiple sclerosis, Huntington’s chorea and spinal cord injuries. Reports that stated the possibility of marijuana smoking and oral THC to relieve nocturnal spasm and spasticity that has to do with spinal cord injuries and multiple sclerosis. According to animal studies, cannabinoids have been effective as anticonvulsants that are specifically important in partial and generalized tonic-clonic seizures.
Cannabinoids had been studied and shown to inhibit tumor angiogenesis in mice that have gliomas by minimizing the expression of different genes that are related to the vascular endothelial growth factor (VEGF) pathway. It works by adding the potency of ceramide, a fat molecule.

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